KumiChemBeta
Accelerating RNA
Therapeutics with AI
Notification
Demonstration only.
Not the final design.
Lets start with KumiChem and find a new drug!
ASO design
Benchmark-evaluated agents are capable of identifying FDA-approved drug candidates (nucleic acid sequences, proteins, or small molecules) as well as discovering novel drugs, further extending their potential for real-world drug discovery.
Data Curation
A MetaAgent achieves infinite memory by batch-processing unlimited items and synthesizing their summaries, maintaining awareness of all content without context constraints
Therapeutic Focus
Where RNA therapeutics unlock new possibilities
Rare Disease
Patients face rapid, life-threatening decline while effective treatments remain scarce or out of reach.
Target root genetic causes directly
Cardiometabolic
Millions face preventable heart attacks, strokes, and organ failure while long-term control remains inadequate.
Precise molecular intervention
Oncology
Many tumors are driven by "undruggable" mutations that traditional small-molecule therapies cannot reach.
Silence disease genes at their source
Neurology
Neurodegenerative diseases progress relentlessly with limited options to modify underlying pathology.
Cross the blood-brain barrier
Start with a simple prompt
Design siRNA for TTR mRNA
Also try: PCSK9 ALAS1 HAO1 ANGPTL3
Target Identification Agent
Identify splice sites, exon junctions, and accessible mRNA regions. Map cryptic splice variants and predict splice-switching targets for exon skipping or inclusion
Splicing & accessibility analysis
Binding Prediction Agent
Predict knockdown efficacy using transformer models. Screen whole transcriptome for seed region (pos 2-8) complementarity.
Efficacy & off-target screening
Structure Folding Agent
Predict siRNA duplex stability and guide strand selection based on 5′ terminal thermodynamic asymmetry.
Secondary structure prediction
Optimization Agent
Apply 2′-OMe, 2′-F, and phosphorothioate modifications for stability. Design GalNAc conjugation for hepatocyte delivery.
Chemical modifications
Optimized Lead Candidates
24 candidates ranked by efficacy, safety, and IP clearance
Ready for synthesis
In vitro validation
5 candidates validated by the real-world assays
to provide the most robust results
KumiChem Automating AIDD workflows
Knowledge - Data - Models - People
For who?
No matter who you are in the world of drug discovery,
we're here to help you move faster, work smarter, and explore further
For Pharma Teams
Want to boost productivity on existing targets or explore brand-new ones?
Our smart AI tools help you accomplish more, from target validation to ligand design, with speed and confidence.
For PIs & University Labs
Bring the power of AI into your everyday research. Our tools are easy to adopt, flexible, and designed to supercharge your lab's discovery workflows.
For Curious Minds & Learners
Just getting started or looking to stay up to date? Dive into the latest in drug discovery and AI with resources that make complex science simple and exciting.
Find the Best Solutions
Our system explores vast chemical and biological spaces, compares strategies, and recommends optimal paths — so you can make smarter decisions, faster.
Seamless & Scalable Workflows
Easily plug into your existing processes. Whether you're running a single experiment or scaling across projects, our platform flexes to your needs.
Collaboration-Ready
We've already begun working with real-world labs to co-create smarter solutions for delivering better medicines — faster. Now, we're looking for ambitious, like-minded partners to collaborate with and grow together.
KumiChem Automating AIDD workflows
Knowledge - Data - Models - People
For who?
No matter who you are in the world of drug discovery, we're here to help you move faster, work smarter, and explore further
For Pharma Teams
Want to boost productivity on existing targets or explore brand-new ones?
Our smart AI tools help you accomplish more, from target validation to ligand design, with speed and confidence.
For PIs & University Labs
Bring the power of AI into your everyday research. Our tools are easy to adopt, flexible, and designed to supercharge your lab's discovery workflows.
For Curious Minds & Learners
Just getting started or looking to stay up to date? Dive into the latest in drug discovery and AI with resources that make complex science simple and exciting.
Find the Best Solutions
Our system explores vast chemical and biological spaces, compares strategies, and recommends optimal paths — so you can make smarter decisions, faster.
Seamless & Scalable Workflows
Easily plug into your existing processes. Whether you're running a single experiment or scaling across projects, our platform flexes to your needs.
Collaboration-Ready
We've already begun working with real-world labs to co-create smarter solutions for delivering better medicines — faster. Now, we're looking for ambitious, like-minded partners to collaborate with and grow together.
News
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FAQ
What tasks can be performed with the KumiChem™ platform?
The KumiChem™ platform is designed to support a wide range of practical, AI-driven tasks in drug discovery and development.
Some examples like: QSAR modeling, ASO (Antisense Oligonucleotide) design, data curation (cleaning, organizing, and validating chemical and biological datasets for more robust model training), custom model training (building tailored machine learning models using proprietary or domain-specific data to solve unique R&D challenges)
How is KumiChem™ different from other platforms?
Who should use KumiChem™ platform?
How can I get early access to KumiChem™?
Didn't find the answer to your question?
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FAQ
What tasks can be performed with the KumiChem™ platform?
The KumiChem™ platform is designed to support a wide range of practical, AI-driven tasks in drug discovery and development.
Some examples like: QSAR modeling, ASO (Antisense Oligonucleotide) design, data curation (cleaning, organizing, and validating chemical and biological datasets for more robust model training), custom model training (building tailored machine learning models using proprietary or domain-specific data to solve unique R&D challenges)